Association of the E23K polymorphism in the KCNJ11 gene with gestational diabetes mellitus
نویسندگان
چکیده
منابع مشابه
the study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region
چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولE23K polymorphism of the KCNJ11 gene in Korean children with type 1 diabetes.
BACKGROUND This study was undertaken to evaluate the association of the E23K polymorphism of KCNJ11 and type 1 diabetes in a Korean population. METHODS Clinical variables from 70 Korean children with type 1 diabetes were analyzed. Patients' DNA was screened for the E23 locus in the KCNJ11 gene. Each genotype frequency and clinical characteristics according to the genotypes were compared betwe...
متن کاملAssociation Between KCNJ11 Gene E23K Polymorphism and Body Composition Together with its Response to Endurance Training
OBJECTIVE To explore the Association between KCNJ11 gene E23K polymorphism of Chinese and body composition together with its response to endurance training. METHOD 102 biologically unrelated Han nationality male new recruits from northern China volunteered to execute a 5000-m running programme, and the intensity is 95-105% individual lactate threshold. The protocol was lasted for 18 weeks, th...
متن کاملAssociation of the KCNJ11 variant E23K with type 2 diabetes in Indo-Trinidadians.
OBJECTIVE To examine the effect of genetic variation in KCNJ11 on the risk of Type 2 diabetes mellitus in Trinidadians. METHODS The coding and bordering intron-exon regions of the KCNJ11 gene were sequenced in 168 diabetic and 61 non-diabetic subjects who historically were thought to be of South Asian Indian ancestry as well as 66 diabetic and 59 non-diabetic subjects of African ancestry. All...
متن کاملG22A Polymorphism of Adenosine Deaminase and its Association with Biochemical Characteristics of Gestational Diabetes Mellitus in an Iranian Population
Adenosine deaminase (ADA) is an important regulator of insulin action. The single nucleotide polymorphism (SNP) G22A in the ADA gene decreases enzymatic activity of ADA. The aim of this study was to investigate the relationship between the SNP G22A and blood glycemic control, insulin resistance, and obesity of gestational diabetes mellitus (GDM) patients in an Iranian population. SNP G22A was d...
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ژورنال
عنوان ژورنال: Diabetologia
سال: 2005
ISSN: 0012-186X,1432-0428
DOI: 10.1007/s00125-005-0035-0